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Mn is surrounded by an N 2 O 2 donor set of salen ligands in a nearly square planar arrangement around the metal center (Fig

doi: 10.1371/journal.pone.0094891 265 WuQLiuMCYangJWangJFZhuYH

A recent screening-based study has identified several promising SARM1 inhibitors, including non-competitive inhibitors such as berberine chloride and zinc chloride 233 , suggesting the presence of an allosteric binding pocket that can be targeted for therapeutic development

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